Windows 10 will be fully supported once officially released including the HIPS feature
please find more info regarding Windows 10 support on the ESET Windows 10 landing page http://www.eset.com/int/windows10-compatibility-free-update/
The upgrade process for both home and business users is also well described in the http://kb.eset.com/esetkb/index?page=content&id=SOLN3747# KB article
Peter Randziak
(ESET employee)